DNA Vaccines
نویسندگان
چکیده
منابع مشابه
DNA vaccines
Since the introduction of DNA vaccines two decades ago, this attractive strategy has been hampered by its low immunogenicity in humans. Studies conducted to improve the immunogenicity of DNA vaccines have shown that understanding the mechanism of action of DNA vaccines might be the key to successfully improving their immunogenicity. Our current understanding is that DNA vaccines induce innate a...
متن کاملDNA vaccines
A new tool, ‘naked DNA’, has recently become available to those involved in vaccine development. It shows great promise for both the improvement of existing vaccines and the development of vaccines against disease targets for which there are so far no effective vaccines. And yet the discovery that naked DNA could be used in vaccination came about more or less by accident, as a result of attempt...
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Administration of genes via DNA or RNA may be considered the next-generation of scientific development following the use of recombinant proteins for prophylactic vaccines or for therapy. The use of DNA vaccines for the generation of immune responses arose from efforts to find immunogens that would be able to overcome some of the limitations of other modalities of vaccination. With the discovery...
متن کاملDNA vaccines: a review
Liu MA (Strasbourg, France and Karolinska Institute, Stockholm, Sweden). DNA vaccines: a review (Review). J Intern Med 2003; 253: 402–410. The DNA vaccines are simple rings of DNA containing a gene encoding an antigen, and a promoter/terminator to make the gene express in mammalian cells. They are a promising new approach for generating all types of desired immunity: cytolytic T lymphocytes (CT...
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Genetic vaccine technology has been considerably developed within the last two decades. This cost effective and promising strategy can be applied for therapy of cancers and for curing allergy, chronic and infectious diseases, such as a seasonal and pandemic influenza. Despite numerous advantages, several limitations of this technology reduce its performance and can retard its commercial exploit...
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ژورنال
عنوان ژورنال: Journal of Health and Translational Medicine
سال: 1998
ISSN: 2289-392X
DOI: 10.22452/jummec.vol3no1.4